EDK
Editome Disease Knowledgebase
Squamous Cell Carcinoma
| Disease name | Squamous Cell Carcinoma |
|---|---|
| Classfication | Cancer |
| Related Enzyme(s) | |
| EFO | EFO:0000707 |
| DOID | 1749 |
| OMIM | |
| NCI | |
| Definition | A carcinoma that derives from squamous epithelial cells. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| IGFBP7 | Human | ADAR1;ADAR2 | 3 | A-to-I | RNA editing in IGFBP7 promotes cell apoptosis in the tumor, but the inadequate A-to-I editing of IGFBP7 may be used by tumor cells to escape the cellular control of proliferation. |
| Enzyme | Full Name | Location | Ensembl | Targets | Related Diseases | Aliases |
|---|---|---|---|---|---|---|
| ADAR1 | Adenosine deaminase, RNA specific | Chr1:154582057..154631560 |
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